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Tumor associated macrophages TAMs one
2020-08-05
Tumor-associated macrophages (TAMs)—one of the limiting factors in anti-tumor immunity—are associated with the poor clinical outcome in most carcinomas, owing to their potential to promote angiogenesis and local invasion, increase the metastasis of tumor cells, and inhibit the anti-tumor immunity.11
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Distribution of DGTS in basidiomycete fungi has been
2020-08-05
Distribution of DGTS in basidiomycete fungi has been demonstrated to be heterogeneous. In certain fungal taxons, such as Agaricales, Polyporales and Russulales, there are species that synthesize and species that do not synthesize DGTS that belong to the same order or even family (Dembitsky, 1996, Va
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Despite the evidence accumulated on the involvement
2020-08-05
Despite the evidence accumulated on the involvement of ETs and their receptors in many pain states, their potential contribution to nociception following SCI has not yet been investigated. Hence, the present study was designed to assess the roles exerted by ETAR and ETBR in neuropathic pain after SC
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There are two genes encoding DEAH RHA helicases in
2020-08-05
There are two genes encoding DEAH/RHA helicases in Escherichia coli (Ec), HrpA (Hypersensitive Response and Pathogenicity A) and HrpB (Hypersensitive Response and Pathogenicity B) [16]. HrpA has been shown to be important in mRNA processing, ATP binding, hydrolysis ability and dsRNA unwinding in vit
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Fusin CXCR serves as a cofactor for entry of some
2020-08-04
Fusin/CXCR-4 serves as a cofactor for entry of some HIV-1 isolates that are T-cell tropic. While some primary HIV-1 isolates are T-tropic and use fusin/CXCR-4 as a cofactor (Doranz et al., 1996), many isolates seem to be M-tropic and use CCR-5 (Deng et al., 1996). To evaluate the importance of CXCR-
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br Introduction Exposure to excessive or uncontrollable stre
2020-08-04
Introduction Exposure to excessive or uncontrollable stress is a major factor associated with a variety of illnesses including psychopathology. Psychosocial stressors may trigger mood disorders or exacerbate the symptoms of schizophrenia as well as contributing to its relapse [1], [2], [3]. In ea
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Research provides ample evidence for
2020-08-04
Research provides ample evidence for an association between changes in opioid signalling and changes in social behaviours in animals. Only a small number of studies attempted to determine whether such associations occur in people as well. Troisi et al. (2011) investigated whether a common polymorphi
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br Discussion The use of carp
2020-08-04
Discussion The use of carp primary cell cultures proved to be a valuable approach to evaluate the piscine immune response. A. hydrophila was a more potent stimulator of NO formation by carp leukocytes compared to commercial LPS often used for leukocyte stimulation (Mustafa and Olson, 1998, Chao e
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We also examined ER and PR expressions
2020-08-04
We also examined ER and PR expressions in MNU-induced mammary tumors and did not see a significant effect of MPA or progesterone on ER and PR expressions. However, ER Ursodiol was significantly decreased in MPA plus TPA treated animals, whereas PR expression was significantly decreased with the addi
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Genistein also protected the neuronal cells in contrast to t
2020-08-04
Genistein, also protected the neuronal Enalapril Maleate australia in contrast to the amyloid toxicity, glutamate and oxidative damages (Sonee et al., 2004; Valles et al., 2008), mainly mediated through the restoration of mitochondrial membrane potential (Gao et al., 2012). Naringin, mainly obtaine
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Next our immunostaining results demonstrated that HOXA and
2020-08-04
Next, our immunostaining results demonstrated that HOXA9 and EPHB4 were co-expressed in trophoblast azidothymidine of first-trimester villi, while EPHB4 hardly existed in normal preterm placenta with lower HOXA9 expression. As we know, villi are a multifunctional structure and the basis of placenta
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Estrogen has been reported to modify synapse
2020-08-04
Estrogen has been reported to modify synapse numbers in several types of neurons. For example, estradiol increases the spine density of hippocampal CA1 pyramidal neurons, neurons in the posterodorsal medial amygdala, and neurons in the ventromedial hypothalamic nucleus (Gould et al., 1990, Calizo an
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br Acknowledgements This research was supported by Slovenian
2020-08-04
Acknowledgements This research was supported by Slovenian Research Agency (ARRS). We thank prof. R. Marinšek Logar for helpful advice, Dr. T. Kranjc for help with data management, N. Vrhovnik and G. Lavrič for technical help with preliminary growth experiments and dr. J. Burkeljca for help with g
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A hydrophobic peptide with molecular weight of Da
2020-08-04
A MI-773 peptide with molecular weight of 5315 Da (Ward, 1998), β-casein f48-91, was observed with low intensity (data not shown) in the sample hydrolysed with GE at 37 °C. The cleavage on C-terminal of Asp with GE was already reported as 1000-fold slower than the cleavage on C-terminal of Glu (Bre
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The relationship of DDR expression to tumor aggressiveness o
2020-08-04
The relationship of DDR1 Spectinomycin dihydrochloride australia to tumor aggressiveness or patient outcome has been investigated for other types of cancer, but these other investigations have typically only considered expression of tDDR1 protein. For example, Quan et al. reported that the DDR1 pro
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