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More recently primary tumor driven generation of
2019-05-18
More recently, primary tumor driven generation of a bone pre-metastatic niche was observed in a mouse model of estrogen receptor-negative breast cancer metastasis. Specifically, lysyl oxidase (LOX) secreted into the circulation from hypoxic primary breast tumors disrupted bone homeostasis, thereby i
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br To see how the
2019-05-18
To see how the quantity of osteosarcoma in vitro studies developed overtime, we set out to systematically identify all the drugs that have been tested on osteosarcoma sirolimus solubility in vitro in the past two decades. A PubMed search strategy was compiled which can be found in Supplementary d
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br Genetic basis for atrial standstill br
2019-05-18
Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an
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Concern about the effects on health of chemical
2019-05-18
Concern about the effects on health of chemical exposure to e-waste and e-waste recycling is increasing despite the paucity of solid research. Reported adverse effects include: fetal loss, prematurity, low birthweight, and congenital malformations; abnormal thyroid function and thyroid development;
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Paying now rather than forever has never been
2019-05-18
Paying now rather than forever has never been as relevant as a global health solution to the HIV pandemic than in 2013. The relative success of the ongoing replenishment session for the Global Fund is a positive signal, although still insufficient considering the evidence-based targets that are set
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br VIII Si atendemos a
2019-05-18
VIII. Si atendemos buy BB-94 que Pablo del Prado en su Directorio espiritual, todavía en el año de 1650, incorporaba numerosas oraciones para la comunión espiritual indígena, junto a recomendaciones sobre la exclusión de la efectiva, no parece probable que se alcanzara nunca una normalización del
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Esta autonom a junto a su prop sito
2019-05-18
Esta autonomía, junto AM966 su propósito de cambio social y su propuesta de una novedosa perspectiva sobre la política, convierte a los movimientos sociales en una particular fuente de conflicto, incluso en el contexto de estos países estudiados. La conflictividad es uno de los ejes presentes en las
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br Methods br Results A total of
2019-05-17
Methods Results A total of 2136 cases, including 614 controls, and 707 LAA, 375 SVO, and 440 HICH cases, were enrolled in this study. Clinical parameters between the control individuals and patients with different stroke subtypes are listed in Table 1. The average age and serum HDL-C level wer
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Introduction Atrial fibrillation AF is
2019-05-17
Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice. The number of people with AF in the United States is currently estimated at 2.4 million, and the projected number with AF may exceed 10 million by 2050 [1,2]. Treatment for AF is also an im
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A quadripolar mapping catheter was
2019-05-17
A quadripolar mapping catheter was placed along the RV septum, and a 3.5mm bidirectional open irrigated mapping catheter (ThermoChool SF®, Biosense Webster, Johnson׳s & Johnson׳s, Diamond Bar, CA, US) was inserted retrogradely into the LV. An electroanatomical substrate map created using the CARTO3®
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br Results The baseline characteristics
2019-05-17
Results The baseline characteristics of the study patients are shown in Table 1. The tachycardia hdac inhibitor length was 350±95ms. To make the tachycardia sustained and stable, isoproterenol was infused in four patients. The activation map during AT was created by sampling from 152±28 RA point
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br de Hern n Lara
2019-05-17
de Hernán Lara Zavala se suma al acervo literario de novelas históricas de México. En los albores del México independiente, la novela histórica representó una vía de exploración y defini-ción del “ser nacional”. A casi dos siglos de distancia la novela histórica ocupa un lugar central en la produc
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De acuerdo con los planteamientos
2019-05-17
De acuerdo con los planteamientos anteriores pensemos en la propuesta que se obtendría desde la obra de Villoro respecto ci-1033 la situación política para un miembro perteneciente a una comunidad indígena, en tanto que además de pertenecer a ella se reconozca como ciudadano del Estado-nación, de es
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Menci n aparte merecen dos rasgos
2019-05-16
Mención aparte merecen dos rasgos en la construcción de este personaje y de su entorno: en primer lugar, sufre de una úlcera en el duodeno que lo hace beber leche en múltiples momentos o mitigar el dolor masticando antiácidos Pepsamar. Mattos se está consumiendo por dentro, en una metáfora que util
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Efforts to estimate the global burden of typhoid fever can
2019-05-16
Efforts to estimate the global burden of typhoid fever can be traced to a meeting of the Pan American Health Organization in 1984 and publication of the outcome in 1986. Although an important first step, the 1984 study was recognised as having a number of limitations including provision of scanty me
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