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It has been noted however that while the process model
2018-10-25
It has been noted, however, that while the process model focuses mainly on implementation success (or failure) of particular emotion regulation strategies, adaptive emotion regulation actually involves a broader repertoire of skills, including flexible strategy selection (e.g. Bonanno and Burton, 20
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A recent framework for conceptualizing ELS posits that adver
2018-10-25
A recent framework for conceptualizing ELS posits that adverse early experiences fall along dimensions of threat and deprivation (McLaughlin et al., 2014; Sheridan and McLaughlin, 2014). Here, threat is conceptualized as an atypical experience posing a direct physical danger to a developing bace inh
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Risk variants in KIAA and DCDC have recently
2018-10-25
Risk variants in KIAA0319 and DCDC2 have recently been shown to interact with each other and to influence dyslexia phenotypes in a non-additive manner (Powers et al., 2013). This trans-genetic interaction between DCDC2 risk haplotypes and KIAA0319 risk haplotypes is based on the strong linkage diseq
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En el campo del feminismo estructuralista Patricia
2018-10-25
En el campo del feminismo estructuralista, Patricia Hill Collins (2000) fue la primera en hablar de la interseccionalidad como un paradigma; sin embargo, fue Ange Marie Hancock (2007) quien propuso una formalización de este paradigma, entendido como un conjunto que engloba PF2341066 la vez teoría no
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Though the issue is so vibrating
2018-10-25
Though the issue is so vibrating, but strikingly, little academic studies (Gill, 2003; Dhankar and Kumar, 2007; Sehgal and Pandey, 2010; Tiwari and Singla, 2015) have explored the comparative accuracy of these models in India. To my knowledge this Otamixaban is among the few studies that provide la
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In the enrolling studies HOTAIR was investigated in
2018-10-25
In the enrolling studies, HOTAIR was investigated in three studies, MALAT1, PVT1 and Sox2ot were detected in two researches, and with the high levels of the four lncRNAs, the prognosis rate was low in GC. In 2014, Liu et al. revealed that HOTAIR may act as a competitive endogenous RNA (ceRNA), effec
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In cardiac hypertrophy associated with pathological processe
2018-10-24
In cardiac hypertrophy associated with pathological processes, it has been shown that CSCs participate in the reparative processes (Ellison et al., 2013; Leri et al., 2005); however, extensive damage cannot be completely reversed, indicating that the regenerative potential of these stem Tubastatin A
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CD BMSCs formed heterotopic bone
2018-10-24
CD34+ BMSCs formed heterotopic bone in vivo which corroborate their enrichment in osteoprogenitors. While in the present study, we employed CD34 as a marker that defines a specific lineage within BMSCs, it is plausible that CD34 plays a role in osteoblast differentiation. CD34 plays an important rol
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We would like to thank
2018-10-24
We would like to thank the Gene Expression Core Facility in the Department of Pathology at UCLA for array analysis; BSCRC Flow Core staff Jessica Scholes and Felicia Codrea for their help with FACS sorting; Jonathan Carlson for useful discussion; and Jason Ernst for thoughtful comments on the manusc
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In the parenchymal niche found
2018-10-24
In the parenchymal-niche found in the adult anterior lobe, SOX2-positive MLN4924 were more densely connected to each other than in the MCL-niche, and formed dense cell clusters by E-cadherin (Fig. 1). We previously demonstrated that CAR and ephrin-B2 specifically localize at the apical cell membran
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Discussion A genome scale location analysis using published
2018-10-24
Discussion A genome-scale location analysis using published data (Gifford et al., 2013) was performed to identify surface proteins that have promoters occupied by POU5F1(OCT4)/SOX2/NANOG (OSN). In total, 30 (6%) of the 496 proteins identified on the surface of hPSCs have promoters occupied by OSN (
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The NAD dependent protein silent information regulator Sir i
2018-10-24
The NAD-dependent protein silent information regulator 2 (Sir2) is a deacetylase for histones and other proteins and a key regulator of life span in several organisms. Sirtuin (SIRT)1 of the Sirtuin family is the closest homolog of yeast Sir2 in mammals and has critical functions in the regulation o
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br Results br Discussion We undertook this study
2018-10-24
Results Discussion We undertook this study in an attempt to unravel the epigenetic mechanisms involved in the silencing of the FMR1 gene in fragile X syndrome by the use of a fibroblast line carrying an unmethylated full mutation. There have been several attempts to study epigenetic silencing
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The analysis of the transcriptome of
2018-10-24
The analysis of the transcriptome of OXM-treated HSPCs was revealing. First, the data showed very clearly that the mRNA levels of mTERT were not different between treated and untreated animals. In vitro studies by others have shown that OXM can enhance telomerase activity through estrogen receptor-m
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br Experimental Procedures br Author Contributions br Acknow
2018-10-24
Experimental Procedures Author Contributions Acknowledgments Introduction Duchenne muscular dystrophy (DMD) is a severe muscular degenerative disease caused by loss-of-function mutations in the dystrophin gene located on the X chromosome. The dystrophin gene consists of 79 exons, and dis
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